Xylocaine Endotracheal Spray

Xylocaine Endotracheal Spray (10 mg/dose): Laryngeal Desensitizer

Xylocaine Endotracheal Spray is a metered-dose Local Anaesthetic containing lidocaine hydrochloride. While originally approved for human use to numb the respiratory tract during procedures like endoscopies, it is utilized in veterinary medicine on an extra-label basis for dogs and cats. Its primary veterinary application is to desensitize the larynx (voice box) and vocal folds, which helps suppress the cough reflex and prevent spasms during the placement of an endotracheal tube for general anesthesia.

Key Information

• Active Ingredient: Lidocaine hydrochloride (10 mg per metered spray).

• Approved Species (Original Licensing): Human.

• Common Veterinary Species: Dog and Cat (used extra-label).

• Uses: Desensitization of the larynx to facilitate endotracheal intubation, prevention of laryngospasm, and suppression of the cough reflex during respiratory examinations.

• Form: Non-aerosol, metered-dose spray.

• Route of Administration: Topical (specifically oropharyngeal/laryngeal).

Important Safety Note for Cats

Cats are uniquely sensitive to the stimulation of the larynx, making desensitization vital for safe anesthesia. However, they are also highly susceptible to lidocaine toxicity. Because this human-labeled Xylocaine spray delivers a potent 10 mg per dose, even one or two sprays can approach the safe limit for a small cat. Veterinary-specific alternatives often deliver a much lower dose (approximately 2 mg) per spray to provide a wider margin of safety.

Prescription Required

Xylocaine Endotracheal Spray is a prescription-only medication. A valid prescription from a licensed veterinarian is required for purchase. Professional veterinary oversight is mandatory, as the medication is typically administered while the pet is under sedation or the early stages of anesthesia. Your veterinarian will determine the precise number of sprays based on your pet's weight to avoid systemic toxicity, which can impact the central nervous system or heart rhythm.