Selegiline

Selegiline Hydrochloride Tablets (5 mg): MAO Inhibitor for Cognitive and Endocrine Support

Selegiline hydrochloride (also known as l-deprenyl) tablets contain the active ingredient Selegiline, which belongs to a class of drugs called Monoamine Oxidase Inhibitors (MAOIs). While approved for human use, this medication is widely used in veterinary medicine, particularly in dogs and sometimes cats. Selegiline is primarily prescribed for:

• Canine Cognitive Dysfunction Syndrome (CDS): It is the only FDA-approved medication for treating the symptoms of dog dementia, which include disorientation, altered sleep-wake cycles, and changes in interactions. It works by increasing dopamine levels in the brain.

• Canine Cushing's Disease: It is also approved for controlling clinical signs associated with uncomplicated pituitary-dependent hyperadrenocorticism (Cushing's disease) in dogs, where it regulates the production of certain hormones.

Key Information

• Active Ingredient: Selegiline Hydrochloride (5 mg).

• Approved Species (Original Licensing): Human.

• Approved Veterinary Uses (FDA): Canine Cognitive Dysfunction Syndrome and uncomplicated Canine Cushing's Disease.

• Uses: Monoamine Oxidase Inhibitor (Hormones and analogs, Antidepressant, Cognitive Support).

• Form: Tablet.

• Route of Administration: Oral.

Prescription Required

Selegiline hydrochloride is a prescription-only medication. A valid prescription from a licensed veterinarian is required for purchase. Due to significant and potentially dangerous interactions with other medications (including certain antidepressants and some flea/tick products), veterinary oversight is critical. The veterinarian must determine the correct diagnosis, dosage, and monitor the pet for signs of adverse drug reactions.