Misoprostol

Misoprostol Tablets (200 mcg): Gastric Protectant and Anti-Ulcer Agent

Misoprostol tablets contain the active ingredient Misoprostol, a synthetic prostaglandin analog. While primarily approved for human use, veterinarians commonly prescribe this medication on an extra-label basis for dogs, cats, and horses. Misoprostol works by increasing the protective mucus and bicarbonate lining of the stomach and reducing acid secretion, functioning as an Anti-ulcer and Antacid agent. It is often used to prevent or treat gastrointestinal (GI) ulceration, especially in animals receiving high doses of Nonsteroidal Anti-inflammatory Drugs (NSAIDs) or corticosteroids, which can cause gastric side effects.

Key Information

• Active Ingredient: Misoprostol (200 mcg).

• Approved Species (Original Licensing): Human.

• Common Veterinary Species: Dog, Cat, and Horse (used extra-label).

• Uses: Anti-ulcer, Gastric Protectant, and Anti-acid (Digestive Health).

• Form: Hexagonal, white, flat-faced, beveled-edged tablet (scored and engraved “MISO” over “200”).

• Route of Administration: Oral.

Prescription Required

Misoprostol is a prescription-only medication. A valid prescription from a licensed veterinarian is required for purchase. Veterinary supervision is essential for proper dosing and monitoring, as Misoprostol can cause GI side effects like diarrhea and is strictly contraindicated in pregnant animals due to its potential to induce uterine contractions.