Isopto Atropine

Atropine Sulfate Ophthalmic Solution 1%: Mydriatic and Cycloplegic Agent

Atropine Sulfate Ophthalmic Solution is a topical Anticholinergic medication used in veterinary medicine for its Mydriatic (pupil-dilating) and cycloplegic (pain-relieving for ciliary spasms) effects. While originally approved for human use, it is a standard treatment in dogs, cats, and horses on an extra-label basis. Atropine works by blocking the action of acetylcholine, which relaxes the muscles of the iris and the ciliary body. This is particularly beneficial for managing the intense pain associated with uveitis and helping to prevent the iris from sticking to the lens (synechia) during active inflammation.

Key Information

• Active Ingredient: Atropine Sulfate (1%).

• Approved Species (Original Licensing): Human.

• Common Veterinary Species: Dog, Cat, and Horse (used extra-label).

• Uses: Mydriatic and Cycloplegic (used to dilate the pupil and relieve ocular pain associated with uveitis or corneal ulcers).

• Form: Ophthalmic Solution.

• Route of Administration: Ophthalmic (Eye Drops).

Prescription Required

Atropine Sulfate Ophthalmic Solution is a prescription-only medication. A valid prescription from a licensed veterinarian is required for purchase. Professional oversight is essential because Atropine is strictly contraindicated in patients with glaucoma or those predisposed to high intraocular pressure. Additionally, since the solution can travel through the tear ducts to the mouth, some pets (especially cats) may experience significant salivation due to its bitter taste. In horses, prolonged use must be monitored closely for signs of decreased gastrointestinal motility (colic).