Hydroxyzine

Hydroxyzine Hydrochloride Capsules: Antihistamine and Mild Sedative

Hydroxyzine hydrochloride capsules contain the active ingredient Hydroxyzine, a first-generation Antihistamine that also possesses Anxiolytic (anxiety-reducing) and mild sedative properties. While originally approved for human use, this medication is widely prescribed by veterinarians on an extra-label basis for dogs, cats, and horses. Hydroxyzine works by blocking H1 histamine receptors, which helps control symptoms associated with allergic reactions, inflammation, and itchiness. The sedative effect also makes it useful for managing situational anxiety.

Key Information

• Active Ingredient: Hydroxyzine Hydrochloride (available in 10 mg, 25 mg, and 50 mg capsules).

• Approved Species (Original Licensing): Human.

• Common Veterinary Species: Dog, Cat, and Horse (used extra-label).

• Uses: Antihistamine (for allergies, itching, and skin conditions), Anxiolytic/Mild Sedative.

• Form: Capsule.

• Route of Administration: Oral.

Prescription Required

Hydroxyzine hydrochloride is a prescription-only medication. A valid prescription from a licensed veterinarian is required for purchase. This is necessary because, as an extra-label drug, the veterinarian must determine the appropriate dosage for your pet's species, weight, and specific condition (allergic or anxiety-related), while also monitoring for potential side effects such as sedation or interactions with other medications.