Apo-Trazodone

Trazodone Hydrochloride Tablets: Serotonin Antagonist and Reuptake Inhibitor (SARI)

Trazodone is a Serotonin Antagonist and Reuptake Inhibitor (SARI) used to manage various anxiety-related conditions and to provide sedation. While originally approved for human use as an antidepressant, it is widely utilised in veterinary medicine on an extra-label basis for dogs and cats. It works by increasing serotonin levels in the brain while blocking specific serotonin receptors, resulting in a calming effect. Trazodone is particularly valued for its rapid onset of action compared to other behavioural medications, making it ideal for situational stress or short-term calming needs.

Key Information

• Active Ingredient: Trazodone hydrochloride.

• Approved Species (Original Licensing): Human.

• Common Veterinary Species: Dog and Cat (used extra-label).

• Uses: Management of situational anxieties (such as fireworks, thunderstorms, or veterinary visits), post-surgical confinement to restrict activity, and as an adjunctive treatment for generalised anxiety disorders.

• Form: Round, white, biconvex, scored tablet.

• Route of Administration: Oral.

Prescription Required

Trazodone is a prescription-only medication. A valid prescription from a licensed veterinarian is required for purchase. Professional veterinary oversight is essential to determine the appropriate dose, as the sedating effects can vary significantly between individual patients. It is important to discuss all other medications your pet is taking with your veterinarian, as trazodone can interact with other drugs that affect serotonin levels.