Apo-Allopurinol

Allopurinol Tablets (300 mg): Uric Acid Reducer for Bladder Stone Management

Allopurinol is a medication classified as a xanthine oxidase inhibitor, originally approved for the treatment of gout in humans (Antigout). In veterinary medicine, it is used on an extra-label basis, primarily in dogs, to manage and prevent the formation of specific types of bladder stones known as urate uroliths. Allopurinol works by reducing the production of uric acid in the body. It is most commonly prescribed for breeds genetically predisposed to urate stones, such as Dalmatians, or for dogs with liver shunts (portosystemic shunts) that interfere with normal uric acid metabolism.

Key Information

• Active Ingredient: Allopurinol (300 mg).

• Approved Species (Original Licensing): Human.

• Common Veterinary Species: Dog (used extra-label).

• Uses: Prevention and dissolution of ammonium urate uroliths (bladder stones) and management of Leishmaniasis (a parasitic disease).

• Form: Round, orange, scored tablet.

• Route of Administration: Oral.

Prescription Required

Allopurinol is a prescription-only medication. A valid prescription from a licensed veterinarian is required for purchase. Professional supervision is essential because Allopurinol must be used in conjunction with a specific low-purine diet. If used incorrectly or without the proper diet, it can lead to the formation of a different type of stone called xanthine stones. Your veterinarian will need to perform regular urinalysis and potentially ultrasound or X-ray monitoring to ensure the medication is working safely and effectively for your dog.